Describes trauma-focused evidence-based treatments (EBT) for children and teens who develop traumatic stress reactions, with specific applications to familial deaths during COVID-19 for 1) young children; 2) American Indian and Alaskan Native families; 3) Black and Latino/Latina adolescents with adjunct peer support components; and 4) diverse youth provided via telehealth. To date, more than 800,000 individuals in the US have died from COVID-19 and more than 140,000 children and teens have lost parents or primary caregivers to COVID-19-related deaths. Many of these youth are at heightened risk for developing traumatic stress reactions to these deaths.